Practitioners in the vanguard of new economic thinking will also find plenty of useful information in this path-breaking book.

This essay is composed of five stories written by practicing physicians about their patients. Each clinical story describes a challenging ethical condition–potential abuse of medical power, gravely ill and probably over-treated newborns, iatrogenic narcotic addiction, deceived dying people. Rather than singling out one ethical conflict to resolve or adjudicate, the authors attempt, through literary methods, to grasp the singular experiences of their patients and to act according to the deep structures of their patients' lives. Examining these five stories with simple (...) literary tools–attention to narrative frames, time, plot, and desire–reveals the mechanisms through which acts of writing and reading contribute to clinical clarity and ethical actions. (shrink)

In this essay we develop and argue for the adoption of a more comprehensive model of research ethics than is included within current conceptions of responsible conduct of research (RCR). We argue that our model, which we label the ethical dimensions of scientific research (EDSR), is a more comprehensive approach to encouraging ethically responsible scientific research compared to the currently typically adopted approach in RCR training. This essay focuses on developing a pedagogical approach that enables scientists to better understand and (...) appreciate one important component of this model, what we call intrinsic ethics . Intrinsic ethical issues arise when values and ethical assumptions are embedded within scientific findings and analytical methods. Through a close examination of a case study and its application in teaching, namely, evaluation of climate change integrated assessment models, this paper develops a method and case for including intrinsic ethics within research ethics training to provide scientists with a comprehensive understanding and appreciation of the critical role of values and ethical choices in the production of research outcomes. (shrink)

The National Science Foundation's Second Merit Criterion, or Broader Impacts Criterion , was introduced in 1997 as the result of an earlier Congressional movement to enhance the accountability and responsibility as well as the effectiveness of federally funded projects. We demonstrate that a robust understanding and appreciation of NSF BIC argues for a broader conception of research ethics in the sciences than is currently offered in Responsible Conduct of Research training. This essay advocates augmenting RCR education with training regarding broader (...) impacts. We demonstrate that enhancing research ethics training in this way provides a more comprehensive understanding of the ethics relevant to scientific research and prepares scientists to think not only in terms of responsibly conducted science, but also of the role of science in responding to identified social needs and in adhering to principles of social justice. As universities respond to the mandate from America COMPETES to “provide training and oversight in the responsible and ethical conduct of research”, we urge institutions to embrace a more adequate conception of research ethics, what we call the Ethical Dimensions of Scientific Research, that addresses the full range of ethical issues relevant to scientific inquiry, including ethical issues related to the broader impacts of scientific research and practice. (shrink)

In this essay we develop and argue for the adoption of a more comprehensive model of research ethics than is included within current conceptions of responsible conduct of research (RCR). We argue that our model, which we label the ethical dimensions of scientific research (EDSR), is a more comprehensive approach to encouraging ethically responsible scientific research compared to the currently typically adopted approach in RCR training. This essay focuses on developing a pedagogical approach that enables scientists to better understand and (...) appreciate one important component of this model, what we call intrinsic ethics . Intrinsic ethical issues arise when values and ethical assumptions are embedded within scientific findings and analytical methods. Through a close examination of a case study and its application in teaching, namely, evaluation of climate change integrated assessment models, this paper develops a method and case for including intrinsic ethics within research ethics training to provide scientists with a comprehensive understanding and appreciation of the critical role of values and ethical choices in the production of research outcomes. (shrink)

In the atavistic model of cancer progression, tumor cell dedifferentiation is interpreted as a reversion to phylogenetically earlier capabilities. The more recently evolved capabilities are compromised first during cancer progression. This suggests a therapeutic strategy for targeting cancer: design challenges to cancer that can only be met by the recently evolved capabilities no longer functional in cancer cells. We describe several examples of this target‐the‐weakness strategy. Our most detailed example involves the immune system. The absence of adaptive immunity in immunosuppressed (...) tumor environments is an irreversible weakness of cancer that can be exploited by creating a challenge that only the presence of adaptive immunity can meet. This leaves tumor cells more vulnerable than healthy tissue to pathogenic attack. Such a target‐the‐weakness therapeutic strategy has broad applications, and contrasts with current therapies that target the main strength of cancer: cell proliferation. (shrink)

This paper outlines new work in cross-cultural psychology largely drawn from Nisbett, Choi, and Smith (Cognition, 65, 15–32, 1997); Nisbett, Peng, Choi, & Norenzayan, Psychological Review, 108(2), 291–310, 2001; Nisbett, The Geography of Thought: How Asians and Westerners Think Differently...and Why. New York: Free Press 2003), Ji, Zhang and Nisbett (Journal of Personality and Social Psychology, 87(1), 57–65, 2004), Norenzayan (2000) and Peng (Naive Dialecticism and its Effects on Reasoning and Judgement about Contradiction. University of Michigan, Ann Arbor, Michigan 1997) (...) Peng and Nisbett (Cross-Cultural Similarities and Differences in the Understanding of Physical Causality. Paper presented at the Science and Culture: Proceedings of the Seventh Interdisciplinary Conference on Science and Culture, Frankfort, K. Y. 1996), and Peng, Ames, & Knowles (Culture and Human Inference: Perspectives from three traditions. In: D. Matsumoto (Ed.), Handbook of Cross-Cultural Psychology (pp. 1–2). Oxford: Oxford University Press 2000). The paper argues that the findings on cultural influences on inference-making have implications for teaching and education generally, and specifically for the debate on conceptions and misconceptions of Asian students studying in western tertiary institutions around the world. The position defended is that, while there seems to be compelling empirical evidence for intercultural differences in thought patterns, these patterns are, for the most part, insignificant in everyday exchanges, though language and culture might subtlety modulate our inference-making at the margins. Linguistic determinism however is not defended. Nonetheless, the evidence provides food for thought, and it needs to inform the recent debates about international students studying overseas. (shrink)

Background: The division of non-paid labor in heterosexual parents in the West is usually still gender-based, with mothers taking on the majority of direct caregiving responsibilities. However, in same-sex couples, gender cannot be the deciding factor. Inspired by Feinberg’s ecological model of co-parenting, this study investigated whether infant temperament, parent factors (biological relatedness to child, psychological adjustment, parenting stress, and work status), and partner relationship quality explained how first-time gay, lesbian, and heterosexual parents divided labor (childcare and family decision-making) when (...) their infants were four months and 12 months old. We also tested whether family type acted as a moderator. Method: Participants were drawn from [MASKED FOR REVIEW]. Only those who provided information about their biological relatedness (yes or no) to their child (N = 263 parents) were included. When infants were four months (T1), parents completed a password-protected online questionnaire exploring their demographic characteristics including work status and standardized online-questionnaires on task division (childcare and family decision-making), infant temperament, parental anxiety, parental depression, parental stress, and partner relationship satisfaction. When infants were 12-months-old (T2), parents provided information about task division and their biological relatedness to their children. Results: Linear mixed models showed that no factor explained the division of family decision making at T1 and T2. For relative time spent on childcare tasks at T1, biological relatedness mattered for lesbian mothers only: biologically related mothers appeared to spend more time on childcare tasks than did non-related mothers. Results showed that, regardless of family type, parents who were not working or were working part-time at T1 performed more childcare tasks at T1. This was still true at T2. The other factors did not significantly contribute to relative time spent on childcare tasks at T2. Conclusion: We had the opportunity to analyze the division of non-paid tasks in families where parenting was necessarily planned and in which gender could not affect that division. Although Feinberg’s model of co-parenting suggests that various factors are related to task division, we found that paid work outside the home was most important during the first year of parenthood in determining caregiving roles. (shrink)

The purpose of this brief introduction is to describe the origin of the papers here presented and to acknowledge the help of some of the many individuals who were involved in the preparation of this volume. Of the eighteen papers, nine stem from the annual fall colloquium of the Depart ment of Philosophy at the University of Western Ontario held in London, Ontario from November 10 to November 12, 1967. The colloquium was entitled 'Philosophical Logic'. After some discussion, the editors (...) decided to retain that title for this volume. Von Wright's paper 'On the Logic and Ontology of Norms' is printed here after some revision. A. R. Anderson commented on the paper at the colloquium, but his comments here are based upon the revised version of the von Wright paper. The chairman of the session at which von Wright's paper was read and discussed was T. A. Goudge. Aqvist's paper 'Scattered Topics in Interrogative Logic', and Belnap's comments, 'Aqvist's Cor rections-Accumulating Question-Sequences', are printed as delivered. The chairman of the Aqvist-Belnap session was R. E. Butts. Wilfrid Sellars' paper 'Some Problems about Belief' is printed as delivered at the col loquium, but 'Quantifiers, Beliefs, and Sellars' by Ernest Sosa is a revision of his comments at the colloquium. That session was chaired by G. D. W. Berry. Ackermann's paper 'Some Problems oflnductive Logic', as well as Skyrms' comments, are printed as delivered. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:86 GOING OUT THE WINDOW: A COMMENT ON TWEYMAN Whether your scepticism be as absolute and sincere as you pretend, we shall learn bye and bye, when the company breaks up: We shall then see, whether you go out at the door or the window; and whether you really doubt; if your body has gravity, or can be injured by its fall; according to popular opinion, derived from our (...) fallacious senses and more fallacious experience. My paper is divided into two sections. In the first section I will summarize and comment on Stanley 2 Tweyman' s paper and in the second section present an alternative reading of Parts X and XI of the Dialogues. SECTION I In his paper Tweyman claims that, although Philo's argument in Parts I-IX of the Dialogues are Pyrrhonian, in Parts X and XI a major change of strategy occurs in which Pyrrhonian arguments are replaced by hypothetico-deductive ones. Recent scholarship on Hume's Dialogues has revolved around two questions: (1) the identification of the sources and personages of the Dialogues and (2) Hume's attitude toward religion. Tweyman and I agree that Philo speaks for Hume. We differ on the character of Philo's challenge to Cleanthes' experimental theism. Philo's methodological shift in Parts X and XI is said to consist in his presentation of scientific hypotheses for appraisal, in contrast to the alternative hypotheses of the earlier Parts, where sceptical arguments are used to undermine Cleanthes' position. I take it that the scientific hypotheses in question are construed realistically 87 and not instrumentally; they are supposedly true or false and permit deductions to be made from them. The first evidence of the methodological shift, we are told, occurs in Part VIII in which Philo speaks in the third and not the first person, "a clear signal to the reader... that his Pyrrhonism... has now been abandoned." (Tweyman, 77) I find this claim unconvincing since in the majority of instances throughout the passage Philo writes in first-person fashion (D 186). Any detectable changes here seem to me to be purely stylistic in character. Tweyman uses the terms 'scepticism' and 'Pyrrhonism' interchangeably. His account of Pyrrhonism involves two theses, the second of which is derived from the first: (1) scepticism involves suspense of judgment between alternative beliefs; and (2) Philo presents his "position in order to show that the hypothesis advanced by Cleanthes is false." (Tweyman, 76) In his sceptical mode in Parts I-IX Philo makes no truth claim for the hypotheses he sets out. But, according to Tweyman,...this does not establish that Philo is a Pyrrhonian throughout the Dialogues, and that he always supports positions... to argue against the hypothesis advanced by Cleanthes. (Tweyman, 76) Tweyman gives two examples of Philonian scepticism in Parts I-VIII. The first is the debate in Part IV over the deity's relation to the world. Cleanthes contends that the deity is external to his creation, and Philo questions the validity of Cleanthes' causal inferences. (D 160) The second is the argument in Parts VI and VII in which Philo argues that the available data do not support the hypothesis of an intelligent designer. I find the account at this point unexceptionable. 88 The first example in which Philo's arguments become "distinctly un-Pyrrhonian" (Tweyman, 77) is the passage in which Philo details the 'inconveniences' of anthropomorphism. Philo begins by saying:...you can still persevere in your anthropomorphism and assert the moral attributes of the Deity, his justice, benevolence, mercy, and rectitude, to be of the same nature with these virtues in human creatures? (D 198) But, he continues, "the course of nature tends not to human or animal felicity." ( Ibid. ) Cleanthes' has asserted human happiness, a thesis which Philo denies. We are no longer dealing with an alternative hypothesis designed to undermine Cleanthes' account but with "the hypothetico-deductive method for testing Cleanthes' hypothesis." (Tweyman, 78) Part XI divides into the three sections which are each discussed to show that Philo's arguments are not Pyrrhonian. since the argument is similar in all three cases, I will remark only on the discussion of the 'indifference hypothesis,' Philo's argument that... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:86 GOING OUT THE WINDOW: A COMMENT ON TWEYMAN Whether your scepticism be as absolute and sincere as you pretend, we shall learn bye and bye, when the company breaks up: We shall then see, whether you go out at the door or the window; and whether you really doubt; if your body has gravity, or can be injured by its fall; according to popular opinion, derived from our (...) fallacious senses and more fallacious experience. My paper is divided into two sections. In the first section I will summarize and comment on Stanley 2 Tweyman' s paper and in the second section present an alternative reading of Parts X and XI of the Dialogues. SECTION I In his paper Tweyman claims that, although Philo's argument in Parts I-IX of the Dialogues are Pyrrhonian, in Parts X and XI a major change of strategy occurs in which Pyrrhonian arguments are replaced by hypothetico-deductive ones. Recent scholarship on Hume's Dialogues has revolved around two questions: (1) the identification of the sources and personages of the Dialogues and (2) Hume's attitude toward religion. Tweyman and I agree that Philo speaks for Hume. We differ on the character of Philo's challenge to Cleanthes' experimental theism. Philo's methodological shift in Parts X and XI is said to consist in his presentation of scientific hypotheses for appraisal, in contrast to the alternative hypotheses of the earlier Parts, where sceptical arguments are used to undermine Cleanthes' position. I take it that the scientific hypotheses in question are construed realistically 87 and not instrumentally; they are supposedly true or false and permit deductions to be made from them. The first evidence of the methodological shift, we are told, occurs in Part VIII in which Philo speaks in the third and not the first person, "a clear signal to the reader... that his Pyrrhonism... has now been abandoned." (Tweyman, 77) I find this claim unconvincing since in the majority of instances throughout the passage Philo writes in first-person fashion (D 186). Any detectable changes here seem to me to be purely stylistic in character. Tweyman uses the terms 'scepticism' and 'Pyrrhonism' interchangeably. His account of Pyrrhonism involves two theses, the second of which is derived from the first: (1) scepticism involves suspense of judgment between alternative beliefs; and (2) Philo presents his "position in order to show that the hypothesis advanced by Cleanthes is false." (Tweyman, 76) In his sceptical mode in Parts I-IX Philo makes no truth claim for the hypotheses he sets out. But, according to Tweyman,...this does not establish that Philo is a Pyrrhonian throughout the Dialogues, and that he always supports positions... to argue against the hypothesis advanced by Cleanthes. (Tweyman, 76) Tweyman gives two examples of Philonian scepticism in Parts I-VIII. The first is the debate in Part IV over the deity's relation to the world. Cleanthes contends that the deity is external to his creation, and Philo questions the validity of Cleanthes' causal inferences. (D 160) The second is the argument in Parts VI and VII in which Philo argues that the available data do not support the hypothesis of an intelligent designer. I find the account at this point unexceptionable. 88 The first example in which Philo's arguments become "distinctly un-Pyrrhonian" (Tweyman, 77) is the passage in which Philo details the 'inconveniences' of anthropomorphism. Philo begins by saying:...you can still persevere in your anthropomorphism and assert the moral attributes of the Deity, his justice, benevolence, mercy, and rectitude, to be of the same nature with these virtues in human creatures? (D 198) But, he continues, "the course of nature tends not to human or animal felicity." ( Ibid. ) Cleanthes' has asserted human happiness, a thesis which Philo denies. We are no longer dealing with an alternative hypothesis designed to undermine Cleanthes' account but with "the hypothetico-deductive method for testing Cleanthes' hypothesis." (Tweyman, 78) Part XI divides into the three sections which are each discussed to show that Philo's arguments are not Pyrrhonian. since the argument is similar in all three cases, I will remark only on the discussion of the 'indifference hypothesis,' Philo's argument that... (shrink)

In a recent series of articles, J. P. Moreland has attempted to revive the idea that bare particulars are indispensable for individuating concrete particulars. The success of the project turns on Moreland's proposal that while bare particulars are indeed 'partially clad'--that is, exemplify at least some properties--they are nevertheless 'bare' in that they lack internal constituents. I argue that 'partially clad' bare particulars (PCBPs) are impervious not only to traditional objections, but also those recently urged in this journal by D. (...) W. Mertz. The real problem with Moreland's view, I contend, is that together with his containment model of predication, it leads to the unwanted conclusion that PCBPs actually contain themselves as constituents, thereby ensnaring them in a vicious (individuative) circularity. (shrink)